都城鍼灸ジャーナル

宮崎県都城市で鍼灸師をしている岩元英輔(はりきゅうマッサージReLife)です。読んだ論文を記録するためのブログです。当院のホームページ https://www.relife2019.jp/index.html しんきゅうコンパス https://www.shinq-compass.jp/salon/detail/33749

灸刺激によるセロトニンとドーパミン

2005 Dec;30(12):1607-13.
 doi: 10.1007/s11064-005-8839-3.

Effect of moxibustion on dopaminergic and serotonergic systems of rat nucleus accumbens

 
 
 
 
Table 1 鍼灸刺激によるセロトニン量の変化.
著者 対象 測定部位 刺激 方法 結果
Aihui Li(2011) rat 脊髄 鍼 ↑
Zhang Y(2011) rat 脊髄 鍼 ↑
Wu JC(2010) rat 背側縫線核 鍼 ↓
Qiao LM(2010) rat 脊髄 鍼 ↑
Guo ZL(2008) rat 縫線核 鍼 ↑
Yuan Q(2007) human 血漿 鍼 ↑
Yoshimoto K(2006) rat 側坐核 鍼 ↑
Fukuda(2005) rat 側坐核 灸 ↑
Lee SH(2002) rat 背側縫線核 鍼 ↓
Wang L(1996) rat 縫線核 鍼 ↑
Fang Z(1996) rat 背側縫線核 鍼 ↑
Zhou Y(1995) rat 視床下部 鍼 ↓
Mo Q(1994) rat 線条体 鍼 ↑
Zhu S(1990) rat 縫線核 鍼 ↑
↑:増加,↓:減少
 

Table 2 鍼灸刺激によるドーパミン量の変化.
著者 対象 測定部位 刺激 方法 結果
Liang Y(2011) rat 視床下部 鍼 ↑
Murotani T(2010) rat 中脳中心灰白質 鍼 ↓
Vu MS(2009) rat 線条体 鍼 ↑
Chuang CM(2007) rat 大脳皮質 鍼 ↑
Zhou SH(2007) human 血中 鍼 ↑
Shem EY(2007) rat 線条体 鍼 ↑
Zhao RJ(2006) rat 側座核 鍼 ↑
Zhao RJ(2005) rat 側座核 鍼 ↓
Fukuda(2005) rat 側坐核 灸 →
Yoon SS(2004) rat 側座核 鍼 ↑
Lin Y(2000) rat 側座核 鍼 ↓
↑:増加,↓:減少,→:変化なし

Fig. 1. Materials and procedure of the moxibustion treatment. (a) Moxa is made from mugwort. (b-1) The moxa, which was refined from mugwort (30 mg). (b-2) We prepared cone-shaped moxa by filling moxa of 1 mg in a pipet tip. Moxa cone of which the diameter was 1 mm at the base and the height was 4 mm. (c) We show a representative temperature curve of a burnt moxa cone. Moxa cone was burnt over 60 s with a peak temperature of 200 C. (d) Moxibustion stimulation was performed without anesthesia and no restriction. (e) The point after the stimulation of 5 moxa cone stimulation revealed mild inflammation. One division of the scale in the figures (b-1, 2) and (e) are equivalent to 1 mm.
 
足三里・腎兪・百会
図2.ドーパミンレベルに対する後肢、腰部、頭頂部の灸の影響。 データは平均±SDを表す(n = 6)8)。 P値は、実験グループ間の差異の統計的有意性を示します(一元配置分散分析)。
 
 
 
Fig. 3. Effect of moxibustion at hindlimb, lumbar and parietal regions on serotonin levels. Data represent mean±SD (n=6)8). P values are for the statistical significance of differences between experimental groups (one-way ANOVA). Dunnett’s multiple comparison test: * P<0.05 compared with the control group.
 
 
Table I. Effect of Moxibustion at Hindlimb, Lumbar and Parietal Regions on DOPAC/DA and 5-HIAA/5-HT Ratios
 
 
2006 Apr;208(4):321-6.
 doi: 10.1620/tjem.208.321.
 
 

Fig. 2. Time course of changes in the extracellular levels of DA in the ACC after acupuncture treatment for 60 min (bar).

Fig. 1. Time-course of changes in the extracellular level of 5-HT in the ACC after acupuncture treatment for 60 min (bar).