Prevalence and Risk Factor Analysis of Constipation After Thoracolumbar Vertebral Compression Fractures

胸腰椎移行部の圧迫骨折(TVCFS)は、

脊椎の圧迫骨折では最も頻度高い場所。

117名のTVCFS患者を対象に、便秘の有病率と危険因子を調査した報告。

対象のうち、83名(70.9%)にローマ分類における便秘が認められた。

危険因子としては、

の使用が関連するとされました。

Demographic and Clinical Characteristic of Patients with Constipation After TVCF (n=117)

	Total Number of Patients (%)	Number of Constipation Patients (%)	Number of Patients without Constipation (%)	χ²	P value
Patients (n)	117 (100%)	83 (70.9%)	34 (29.1%)
Gender				0.003	0.957
Female	96 (82.1%)	68 (81.9%)	28 (82.4%)
Male	21 (17.9%)	15 (18.1%)	6 (17.6)	0.952	0.621
Age
60~69y	66 (56.4%)	48 (57.8%)	18 (53.0%)
70~79 y	36 (30.8%)	26 (31.3%)	10 (29.4%)
≥80 y	15 (12.8%)	9 (10.8%)	6 (17.6%)
Number of fractured vertebrae				0.095	0.953
1	98 (83.8%)	70 (84.3%)	28 (82.4%)
2	10 (8.5%)	7 (8.4%)	3 (8.8%)
≥3	9 (7.7%)	6 (7.2%)	3 (8.8%)
Main fracture segment				0.404	0.817
Thoracic segments (T10 and above)	5 (4.3%)	3 (3.6%)	2 (5.9%)
Thoracic-lumbar segment (T11~L2)	93 (79.5%)	67 (80.7%)	26 (76.5%)
Lumbar segment (L3 and below)	19 (16.2%)	13 (15.7%)	6 (17.6%)
Degree of vertebrae compression				18.019	0.000*
Mild	42 (35.9%)	20 (24.1%)	22 (64.7%)
Moderate	46 (39.3%)	37 (44.6%)	9 (26.5%)
Severe	29 (24.8%)	26 (31.3%)	3 (8.8%)
TCM syndrome type				2.583	0.108
Qi stagnation/blood stasis	106 (90.6%)	78 (94.0%)	28 (82.4%)
Liver/kidney insufficiency	11 (9.4%)	5 (6.0%)	6 (17.6%)
Use of painkillers				0.016	0.900
No	54 (46.2%)	38 (45.8%)	16 (47.1%)
Yes	63 (53.8%)	45 (54.2%)	18 (52.9%)
Diabetes				0.007	0.932
No	102 (87.2%)	73 (88.0%)	29 (85.3%)
Yes	15 (12.8%)	10 (12.0%)	5 (14.7%)
Use of Zengyechengqi decoction				19.570	0.000*
No	90 (76.9%)	73 (88.0%)	17 (50%)
Yes	27 (23.1%)	10 (12.0%)	17 (50%)